This course aims to provide students with the latest information about the bio-personal and social relevance of sleeping. The fact that quality of sleep the night before is the best indicator of daytime performance, is what emphasizes personal relevance. This course focuses on the neurobiological foundations of sleep control. This course covers cellular-level explanations of sleep deprivation and jetlag. It also discusses how substances like nicotine, alcohol, caffeine, and caffeine can affect sleep and wakefulness. Second section covers the sleep-dependent modifications in physiology, and medicine for sleep disorders. Disorders such as excessive sleepiness and insomnia will receive special attention. Sleep deprivation can lead to obesity and a decline in immune function. All causes of death are more common between 4:45 and 6:06 a.m. This second section highlights the importance of sleep in preventive medicine. In the last section, we will discuss the societal importance of sleep. Operator-error can cause serious safety and health problems in a technologically advanced society. It is known that fatigue-related performance declines have been implicated in the causes of nuclear power plant accidents, transport disasters and medical mistakes.